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Flutamide - CAS# 13311-84-7 Catalog No.:M7030-2 1021/ml100293q

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Description

1021/ml100293q

potent and selective inhibitor of wild-type LRRK2 and the G2019S mutant (IC50 for LRRK2-wild-type ~20

1-4H3/t19-/m0/s1

GF-109203X inhibited GSK-3 in vitro

1014691-61-2

Flutamide - CAS# 13311-84-7 Catalog No.:M7030-2 1021/ml100293qFlutamide, CAS No. 13311 84 7, also known as SCH13521, is a toluidine derivative and nonsteroidal antiandrogen that is structurally related to bicalutamide and nilutamide. Flutamide and its more potent active metabolite 2 hydroxyflutamide competitively block dihydrotestosterone binding at androgen receptors, forming inactive complexes which cannot translocate into the cell nucleus. Formation of inactive receptors inhibits androgen dependent DNA and

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