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Pixantrone (27 mg/kg) does not worsen pre-existing moderate degenerative cardiomyopathy in doxorubicin-pretreated mice
Molecular Weight: 197
Chemical Name: {[(5-nitrofuran-2-yl)methylidene]amino}urea
InChi: InChI=1S/C11H16ClNO2
Molecular Weight: 359
SAR-100842 13341 Pixantrone (27 mg/kg) does notSAR 100842 is a lysophaphatidic acid 1 (LPA1 Edg 2) receptor inhibitor. SAR 100842 (Compound Example 14) is an Edg 2 receptor inhibitor extracted from patent WO2009135590A1, has an IC50 of <0. 1 M. SAR 100842 (SAR100842) is a lysophaphatidic acid receptor 1 (LPA1) inhibitor, which can be used for the treatment of systemic sclerosis and related fibrotic diseases. In LPAR1 based in vitro inhibition of LPA stimulated Ca2+ flux in a cell based assay, SAR
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