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A-366 is also a potent
twice per day for 4 weeks) treatment can be delivered to mice in concentrations to sufficiently penetrate sMPNST tissue
CAS Number: 134-58-7
Formula: C20H27NO6S
5 to 37 μM
EGFR-IN-1 14 mesylate A-366 is also a potentEGFR IN 1 (compound 24) is an orally active and irreversible L858R T790M mutant selective EGFR inhibitor. EGFR IN 1 potently inhibits Gefitinib resistant EGFR L858R, T790M with 100 fold selectivity over wild type EGFR. EGFR IN 1 displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity. Product information CAS Number: 1625677 63 5 Molecular Weight: 514. 58 Formula: C28H30N6O4 Chemical