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P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist
⁸]decan-2-yl]methyl benzoate
PF-3845 is a fatty acid amide hydrolase (FAAH) inhibitor
It has >100-fold selectivity over other methyltransferases and other non-epigenetic targets
InChiKey: QBIYUDDJPRGKNJ-UHFFFAOYSA-M
Nordihydroguaiaretic acid - CAS# 500-38-9 tabolite Hydroxy Iloperidone P-Glycoprotein inhibitor and potent dopamineEtrasimod, also known as APD334, is a potent, centrally available, functional antagonists of the S1P1 receptor for use as next generation therapeutics for treating multiple sclerosis (MS) and other autoimmune diseases. APD334 has a favorable PK PD profile, producing robust lymphocyte lowering at relatively low plasma concentrations in several preclinical species. APD334 was efficacious in a mouse experimental autoimmune encephalomyelitis (EAE) model
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