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IMM-H007 nacipran Toh et al (2015) A

SKU: 86134894850

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Description

Toh et al (2015) A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N6-methyladenosine demethylase FTO

such as mucosal erosions or leakage in the KI mice or nonhuman primates

cell growth

Smiles: CCS(=O)(=O)N1CCN(CC1)C1C=CC(=CC=1)NC1=NC(NC2CC2)=C(C=N1)C(N)=O

A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase

IMM-H007 nacipran Toh et al (2015) AIMM H007, an adenosine derivative, is an activator of AMP Activated Protein Kinase (AMPK). IMM H007 is a potential drug for treating cardiac dysfunction. IMM H007 negatively regulates endothelium inflammation through inactivating NF B and JNK AP1 signaling. IMM H007 inhibits ABCA1 (ATP binding cassette subfamily a member 1) degradation and facilitates its cell surface localization in macrophages, thereby promotes cholesterol efflux. Product

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