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Because of its hydrophobicity and large molecular weight
CB-5083 appears to exhibit greater potency over current proteasome inhibitors that further validate targeting p97 and protein homeostasis in the treatment of cancer
The IC50 value of Vactosertib on pSmad3 in 4T1 cells is 10-30 nM
5-dimethyl-1-phenyl-1H-pyrrol-3-yl)vinyl)-6-(dimethylamino)-1-methylquinolin-1-ium 4
Sheahan TP
m-PEG7-azide eta-L-galactopyranosylorientin Because of its hydrophobicity andm PEG7 azide is a PEG based PROTAC linker can be used in the synthesis of PROTACs. Product information CAS Number: 208987 04 6 Molecular Weight: 365. 42 Formula: C15H31N3O7 Chemical Name: 22 azido 2,5,8,11,14,17,20 heptaoxadocosane Smiles: COCCOCCOCCOCCOCCOCCOCCN=[N+]=[N ] InChiKey: KKPCQLXBYKYWQE UHFFFAOYSA N InChi: InChI=1S C15H31N3O7 c1 19 4 5 21 8 9 23 12 13 25 15 14 24 11 10 22 7 6 20 3 2 17 18 16 h2 15H2,1H3 Technical Data Appearance: Solid
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