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16(1):373-379
Morrison RD
InChiKey: XEIKWJLAIULVMY-YNQICIJSSA-N
1021/ml500367g
InChi: InChI=1S/C16H16N2O6/c19-12(20)7-17-15(22)13-14(21)10-3-1-2-4-11(10)18(16(13)23)24-8-9-5-6-9/h1-4
L-701324 tone isopropyl 16(1):373-379L 701324 is an orally active and long acting anticonvulsant with high affinity and selectivity for the glycine site on the NMDA receptor. Target: NMDA ReceptorL 701324 is a potent, active anticonvulsant with a reduced propensity to activate mesolimbic dopaminergic systems in rodents. L 701324 exhibits a beneficial action in the animal model of parkinsonian rigidity, but not that of parkinsonian akinesia. L 701324 (2. 5 40 mg kg, i. p.) dose
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