ACAT-IN-6 5428 The acute transcriptional response to

The acute transcriptional response to SW044248 in sensitive HCC4017 cells correlated significantly with inhibitors of topoisomerases and SW044248 inhibited topoisomerase 1 (Top1) but not topoisomerase 2

Molecular Weight: 635

Canonica GW

Smiles: OC1C=CC(=CC=1)C1SC2=CC(=CC=C2C=1C(=O)C1C=CC(=CC=1)OCCN1CCCCC1)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

High WM Jr

ACAT-IN-6 5428 The acute transcriptional response toACAT IN 6 is an acyl Coenzyme A: cholesterol acyltransferase (ACAT) inhibitor extracted from patent EP1236468A1, example 200. ACAT IN 6 potently inhibits NF B mediated transcription. Product information CAS Number: 454203 45 3 Molecular Weight: 573. 79 Formula: C31H47N3O5S Chemical Name: 2 amino N [3, 5 bis(propan 2 yl) 4 [({2 [2, 4, 6 tris(propan 2 yl)phenyl]acetamido}sulfonyl)oxy]phenyl]acetamide Smiles: