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CAS Number: 135459-87-9
Magolda RL
8(19):31065-31078
2000 Oct 27
InChi: InChI=1S/C17H16ClN3O/c18-16-7-5-15(6-8-16)17(22
GW806742X hydrochloride thenolide) CAS Number: 135459-87-9GW806742X hydrochloride, an ATP mimetic and a potent MLKL (Mixed Lineage Kinase Domain Like protein) inhibitor, binds the MLKL pseudokinase domain with a Kd of 9. 3 M. GW806742X hydrochloride has activity against VEGFR2 (IC50=2 nM). GW806742X hydrochloride retards MLKL membrane translocation and inhibits necroptosis. Product information Molecular Weight: 610. 01 Formula: C25H23ClF3N7O4S Chemical Name: 3 {4 [methyl({2 [(3
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