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FD-IN-1 eceptor antagonists-2 Hormonal impact of the 17α-hydroxylase/C17

SKU: 82914124320

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Description

Hormonal impact of the 17α-hydroxylase/C17

2(6):1492-7

Formula: C17H18N4O2

Indocyanine Green

Ashby CR Jr

FD-IN-1 eceptor antagonists-2 Hormonal impact of the 17α-hydroxylase/C17FD IN 1 (Compound 12) is an orally bioavailable and selective factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD IN 1 also inhibits factor XIa (FXIa) and Tryptase 2 with IC50s of 7. 7 and 6. 5 M, respectively. Product information CAS Number: 1646682 14 5 Molecular Weight: 377. 43 Formula: C23H23NO4 Chemical Name:

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